The potential uses of preexposure prophylaxis for HIV prevention among people who inject drugs

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The potential uses of preexposure prophylaxis for HIV prevention among people who inject drugs.

PURPOSE OF REVIEW Oral preexposure prophylaxis (PrEP) has shown HIV preventive efficacy for several key populations at risk for HIV infection including MSM and heterosexual men and women in HIV serodiscordant relationships. An efficacy trial of daily oral tenofovir among people who inject drugs (IDU) is underway in Thailand. RECENT FINDINGS Although efficacy data is pending, there is emerging...

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Cost-Effectiveness of HIV Preexposure Prophylaxis for People Who Inject Drugs in the United States.

Background The total population health benefits and costs of HIV preexposure prophylaxis (PrEP) for people who inject drugs (PWID) in the United States are unclear. Objective To evaluate the cost-effectiveness and optimal delivery conditions of PrEP for PWID. Design Empirically calibrated dynamic compartmental model. Data Sources Published literature and expert opinion. Target Populatio...

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Examining the Potential Role of a Supervised Injection Facility in Saskatoon, Saskatchewan, to Avert HIV among People Who Inject Drugs

Background Research predicting the public health and fiscal impact of Supervised Injection Facilities (SIFs), across different cities in Canada, has reported positive results on the reduction of HIV cases among People Who Inject Drugs (PWID). Most of the existing studies have focused on the outcomes of Insite, located in the Vancouver Downtown Eastside (DTES). Previous attention has not been af...

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HIV among people who inject drugs in Hungary

BACKGROUND Before 2014 (the year of closure of the two largest needle exchange programs in Hungary, which halved the number of available syringes in the country despite increased injecting risk practices) no HIV was reportedly acquired in Hungary among people who inject drugs (PWIDs) who were not also men who had sex with other men (MSM). In 2014, one and in 2015 two non-MSM PWIDs were newly di...

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Preexposure Prophylaxis for HIV Prevention

This interactive feature addresses the diagnosis or management of a clinical case. A case vignette is followed by specific clinical options, none of which can be considered either correct or incorrect. In short essays, experts in the field then argue for each of the options. In the online version of this feature, available at NEJM.org, readers can participate in forming community opinion by cho...

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ژورنال

عنوان ژورنال: Current Opinion in HIV and AIDS

سال: 2012

ISSN: 1746-630X

DOI: 10.1097/coh.0b013e328358e49e